KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHB1
All Species:
27.27
Human Site:
S774
Identified Species:
75
UniProt:
P54762
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54762
NP_004432.1
984
109885
S774
R
Y
L
Q
D
D
T
S
D
P
T
Y
T
S
S
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
P820
L
G
H
S
P
Q
G
P
S
C
L
L
R
W
A
Rhesus Macaque
Macaca mulatta
XP_001115263
984
109811
S774
R
Y
L
Q
D
D
T
S
D
P
T
Y
T
S
S
Dog
Lupus familis
XP_542791
1007
112622
S797
R
Y
L
Q
D
D
T
S
D
P
T
Y
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBF3
984
109863
S774
R
Y
L
Q
D
D
T
S
D
P
T
Y
T
S
S
Rat
Rattus norvegicus
P09759
984
109865
S774
R
Y
L
Q
D
D
T
S
D
P
T
Y
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q07494
984
109166
S774
R
Y
L
Q
D
D
T
S
D
P
T
Y
T
S
S
Frog
Xenopus laevis
Q91571
985
110086
S775
R
Y
L
Q
D
D
T
S
D
P
T
Y
T
S
S
Zebra Danio
Brachydanio rerio
O13146
981
109636
D779
L
S
R
V
L
E
D
D
P
E
A
A
Y
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.1
99.6
95.7
N.A.
98.8
98.8
N.A.
N.A.
89.3
88.9
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65.1
99.9
96.8
N.A.
99.5
99.5
N.A.
N.A.
92.7
93.1
73
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
100
100
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
100
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
78
78
12
12
78
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
23
0
78
0
12
0
0
0
0
0
12
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
12
12
78
0
0
0
0
0
% P
% Gln:
0
0
0
78
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
78
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
12
0
12
0
0
0
78
12
0
0
0
0
78
78
% S
% Thr:
0
0
0
0
0
0
78
0
0
0
78
0
78
12
12
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
78
0
0
0
0
0
0
0
0
0
78
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _